We are currently seeking full-time or part time (at least 32 hours per week) a Medical Monitor* to strengthen our Clinical Development department. You will work in Tübingen, Munich or remote (Germany) in an interdisciplinary environment with colleagues from Germany and the US. Your analytical reasoning and action-oriented style as well as your organization and communication skills will contribute to the team’s success. In this role, you will collaborate closely with clinical departments across our global organization and will contribute to our mission of delivering novel PRAME immunotherapies to patients with cancer. This is a permanent position.

YOUR MISSION

Your main responsibilities will include but are not limited to the following tasks:

Medical and Safety Oversight

• Provide medical oversight for clinical trials from Phase 1 to Phase 3

• In collaboration with Drug Safety, assess (Serious) Adverse Events with regards to causality, expectedness and clinical management - including CIOMS and MedWatch forms

• Serve as primary contact for medical investigator enquiries

• Reviews MPs and other documents related to safety data review

• Lead/ support medical data review meetings, DSMB meeting and other meetings related to patient safety

• Collaborate with Drug Safety on signal detection

Trial conduct and Protocol Compliance

• Provide medical input on trial design and clinical trial protocol development/ amendments

• Review and approve eCRFs

• Provide input for Investigator Brochures

• Ensure eligibility criteria, IMP dosing and management of adverse events, and safety assessments are in line with the clinical trial protocol

• Participate in Protocol Deviation assessments

• Support investigators by addressing protocol-related questions

• Participate in site selection and trainings (e.g., SIVs)

• Contribute to Investigator Meetings and all types of site visits as needed

Regulatory

• Support regulatory filings and responses to regulatory enquiries

• Provide medical expertise for Risk Management Plans

Data review, analysis and interpretation

• Ensure timely medical review of individual and aggregate safety and efficacy data

• Review patient narratives

• Contribute to interpretation of data in early clinical trials

• Contribute to clinical study reports, publications and presentations

YOUR PROFILE

You hold an MD PhD in Biomedical Sciences, or a related field. Prior Experience as a Medical Monitor is required. Experience in oncology and in cell therapy, including clinical development or trial oversight is preferred. We expect a high degree of independent working, attention to detail and problem solving skills. You bring very good communication skills in English; German is a plus. Travel up to 30 % might be required.

WHY US?

We are the global leader in precision targeting of PRAME. Driven by our mission to make an impact on the lives of patients with cancer, we are a committed and inspired team and cherish the collegial, highly motivated, and family-friendly atmosphere within Immatics. Our culture allows for a high level of originality, independent thinking, and initiative. We believe in supporting our employees’ professional and social skills: We enable them to join conferences and trainings as well as to enjoy our Immatics benefits – e.g., job bike, job ticket, Health Programs, childcare benefits, relocation allowance, Company summer and winter events.

NOTICE

*We value diversity and inclusion. Immatics N.V. and all Immatics subsidiaries are equal opportunity employers that evaluate qualified applicants without regard to race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.

ABOUT US

Immatics combines the discovery of true targets for cancer immunotherapies with the development of the right T cell receptors with the goal of enabling a robust and specific T cell response against these targets.
This deep know-how is the foundation for our pipeline of Adoptive Cell Therapies and TCR Bispecifics as well as our partnerships with global leaders in the pharmaceutical industry. We are committed to delivering the power of T cells and to unlocking new avenues for patients in their fight against cancer.